Endothelial Dysfunction in Rheumatoid Arthritis
نویسندگان
چکیده
منابع مشابه
To Study Endothelial Dysfunction in Rheumatoid Arthritis.
BACKGROUND Rheumatoid arthritis (RA) is associated with an increased morbidity and mortality. This excess mortality attributable to cardiovascular events. Endothelial dysfunction represents the earliest stage of atherosclerosis. It can be measured noninvasively by peripheral tests of function, such as pulse wave analysis. OBJECTIVES To evaluate the influence of chronic inflammatory state on e...
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Inflammation, as a feature of rheumatoid arthritis (RA), leads to the activation of endothelial cells (ECs). Activated ECs induce atherosclerosis through an increased expression of leukocyte adhesion molecules. Endothelial dysfunction (ED) is recognized as a failure of endothelial repair mechanisms. It is also an early preclinical marker of atherosclerosis and is commonly found in RA patients. ...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2013
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.113.301490